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Osama Hamdy, M.D., Ph.D., F.A.C.E.


Dr. Hamdy studies the cardiovascular benefits of short and long term weight reduction in obese individuals with and without type 2 diabetes. He also studies the role of body fat distribution in initiation and acceleration of cardiometabolic complications of obesity.  His clinical research also evaluates the effect of weight reduction on circulating cytokines and body fact distribution. Dr. Hamdy and colleagues' research led to the first discovery that obese adults who lost 7 percent of their initial weight had significant improvement in their vascular endothelial function. This improvement may eventually prevent the progression of atherosclerosis and the subsequent risk of coronary artery disease and stroke.


Osama Hamdy, MD, PhD, FACE is the Medical Director of the Obesity Clinical Program, at Joslin Clinic and Director of the Inpatient Diabetes Program.  He is Clinical Investigator and senior adult Endocrinologist at Joslin Diabetes Center and Assistant Professor of Medicine at Harvard Medical School.

Dr. Hamdy is a co-investigator of 2 landmark studies; the National Diabetes Prevention Program and the Look AHEAD (Action for Health in Diabetes) Study.  He translated the successful clinical research results of the lifestyle modifications clinical trials into a clinical practice model: the Why WAIT Program (Weight Achievement and Intensive Treatment), the world's first multidisciplinary clinical practice model for diabetes weight management.

Dr. Hamdy chaired the task force that developed the Joslin New Nutrition Guidelines and is the member of the Nutrition Guidelines Committee of the American Association of Clinical Endocrinologist that created the AACE Nutrition Guidelines for Healthy Americans, the Guidelines for Obesity Management and the Guidelines for Bariatric Surgery. He co-chairs the International Diabetes Nutrition Group that developed the Transcultural Diabetes Nutrition Algorithm (tDNA). Dr. Hamdy is currently leading the effort to improve the quality of diabetes care across the globe through implementing an effective transcultural lifestyle intervention.

Dr. Hamdy has more than 150 peer-reviewed original articles, reviews, chapters, conference abstracts and proceedings. He is on the editorial board of several medical journals including US Endocrinology, Journal of Nutritional Disorders & Therapy and 2-times section editor of the Current Diabetes Report. He is a member of the editorial review board of many scientific medical journals including JAMA, Diabetes Care, Lancet, Obesity Research and the Expert Opinions. He is the author of the Harvard Health Publication “The Diabetes Breakthrough”.


Page last updated: September 19, 2019