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Pilot & Feasibility Studies



As part of the NIH grant that supports Joslin Diabetes Center’s Diabetes and Research Center (DRC), the Pilot & Feasibility (P&F) Program offers funding each year for two studies in the areas of type 1 diabetes, type 2 diabetes or their complications. The P&F awards may be from basic, translational or clinical perspectives. 
The goal of the P&F Program is to encourage research on diabetes and its complications by two target groups: young diabetes researchers who recently became independent and have not yet received significant NIH or other funding, and seasoned investigators either entering the diabetes field for the first time or exploring a completely new direction.
A call for applications is made each year; at this time we plan to have new grants begin January 1.  Two new grants are awarded each year to researchers based either at the Joslin Diabetes Center or at neighboring institutions within Harvard Medical School and affiliated hospitals and Harvard School of Public Health. These awards are typically made for one year, with a second year of funding contingent upon submission of an acceptable progress report. A special effort is made to foster interactions between Joslin DERC investigators and the external P&F Study Program awardees. This includes facilitating access to Joslin DRC cores, an invitation to give a seminar in the Joslin internal research seminar series, and invitations to Joslin retreats and other enrichment activities.
The program has been highly successful since its inception. Projects funded in past years have covered a wide range of topics in the fields of type 1 and type 2 diabetes and their complications, including the control of insulin gene expression, mechanisms of insulin action and resistance, beta cell apoptosis, mechanisms of leptin action and resistance, stem cells, and immunology and autoantigen therapy in type 1 diabetes. The approaches have also been very diverse, covering a broad range of biochemical, molecular and cellular biologic, genetic and clinical strategies. This breadth reflects the interests of Joslin’s diabetes research program as a whole; see more about Joslin’s Research Programs.


Page last updated: September 19, 2019